My PROLASTIN DIRECT® means unmatched support.

PROLASTIN DIRECT was there for 
me—getting PROLASTIN®-C LIQUID approved through my insurance company, setting everything up for
 my home infusions.

—Jesus, actual patient since 2016

PROLASTIN DIRECT: The PROLASTIN-C LIQUID patient support program

Automatic enrollment

People with alpha-1 who are prescribed PROLASTIN-C LIQUID are automatically enrolled in PROLASTIN DIRECT, a comprehensive patient program dedicated to providing personalized support.

Help at every step

From securing insurance coverage to coordinating your infusions and beyond, our PROLASTIN DIRECT patient support experts are there to provide unmatched support every step of the way. Sometimes, your provider may select a specific infusion provider. In that case, the selected infusion provider will work with you on starting your treatment.

Disease management coordinator

PROLASTIN DIRECT can even help you connect with a coordinator at AlphaNet®, a not-for-profit organization dedicated to helping people with alpha-1. You can reach out to AlphaNet if not already connected with a Coordinator.

Better quality of life

In a 2‑year study, patients receiving 12 months of augmentation therapy while enrolled in ADMAPP (97% in PROLASTIN DIRECT®) reported better quality of life and fewer unscheduled doctor visits, hospitalizations, and antibiotic use compared with 12 months of augmentation therapy alone.1 They also had significantly fewer COPD exacerbations (p<0.001) and fewer emergency room visits (p=0.02).

Toya, Jesus, and Heather, actual patients

With PROLASTIN DIRECT, there is help at every step

  • Insurance verification and help completing your prescription processing
  • Pharmacy services, supplies, and delivery to your home or infusion center
  • Infusion coordination with a registered nurse trained in alpha-1 care*
  • Assistance connecting with a coordinator at AlphaNet
  • Access to expert nurses and pharmacists
  • If you are not receiving PROLASTIN-C LIQUID through Accredo specialty pharmacy, connect with your infusion provider.

*Service for at-home infusions patients only

When I was first diagnosed with alpha-1, I was extremely overwhelmed. But when I connected with the PROLASTIN DIRECT program and AlphaNet, it was such a blessing
for me.

—Toya, actual patient since 2016

My schedule, my alpha-1 journey: Seamless support makes treatment work with my life.

Shipping your medicine, scheduling your infusion, and even administering your infusion are all handled by the PROLASTIN DIRECT program. Whether you will receive PROLASTIN-C LIQUID infusions at home or at an infusion center, PROLASTIN DIRECT will help get your medication shipments to the right location.

Getting started with PROLASTIN-C LIQUID

Prescription is sent

Your doctor sends your prescription to the PROLASTIN DIRECT program, which helps you with navigating insurance coverage, choosing where to receive infusions, and more. Sometimes, your provider may select a specific infusion provider. In that case, the selected infusion provider will work with you on starting your treatment.

Representative calls

PROLASTIN DIRECT will call you within 2 business days after receiving your prescription. A representative will verify your insurance, answer any questions you may have, and help complete your prescription processing. It is very important to answer this phone call to get your treatment started. The caller ID may show as “unknown” or “NA” or even “Accredo,” the name of the specialty pharmacy.

Infusion location set

If you would like to receive infusions at home, a nurse from PROLASTIN DIRECT will call to review and confirm your insurance coverage and benefits. They’ll also explain how the program, treatment, and infusions work, and how your medication will be sent. If you choose infusions at an infusion center, the center will call to explain their process.

The PROLASTIN DIRECT Assist Program may help with your copay.

PROLASTIN-C LIQUID is covered by 90%+ of health plans nationwide and those that have commercial insurance may qualify for a $0 copay through the PROLASTIN DIRECT Assist Program. The program may also help with the cost of the deductible, and can provide up to $10,000 per year every year in financial assistance for eligible patients.

PROLASTIN-C LIQUID: Trusted by alpha-1 patients and their doctors.

The #1 prescribed augmentation therapy, PROLASTIN-C LIQUID has been trusted by patients with alpha-1 and their doctors for more than 35 years.

Looking for more information and insights?

Receive tips for living with alpha-1 and PROLASTIN-C LIQUID updates. 

Important Safety Information

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PROLASTIN®-C LIQUID is an alpha1-proteinase inhibitor (human) (alpha1-PI) indicated for chronic augmentation and maintenance therapy in adults with clinical evidence of emphysema due to severe hereditary deficiency of alpha1-PI (alpha1-antitrypsin deficiency).

Limitations of Use

  • The effect of augmentation therapy with any alpha1-PI, including PROLASTIN-C LIQUID, on pulmonary exacerbations and on the progression of emphysema in alpha1-PI deficiency has not been conclusively demonstrated in randomized, controlled clinical trials
  • Clinical data demonstrating the long-term effects of chronic augmentation or maintenance therapy with PROLASTIN-C LIQUID are not available
  • PROLASTIN-C LIQUID is not indicated as therapy for lung disease in patients in whom severe alpha1-PI deficiency has not been established

PROLASTIN-C LIQUID is contraindicated in immunoglobulin A (IgA)-deficient patients with antibodies against IgA or patients with a history of anaphylaxis or other severe systemic reaction to alpha1-PI products.

Hypersensitivity reactions, including anaphylaxis, may occur. Monitor vital signs and observe the patient carefully throughout the infusion. If hypersensitivity symptoms occur, promptly stop PROLASTIN-C LIQUID infusion and begin appropriate therapy.

Because PROLASTIN-C LIQUID is made from human plasma, it may carry a risk of transmitting infectious agents, eg, viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent, and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent. This also applies to unknown or emerging viruses and other pathogens.

The most common adverse reactions during PROLASTIN-C LIQUID clinical trials in >5% of subjects were diarrhea and fatigue, each of which occurred in 2 subjects (6%).

Please see full Prescribing Information for PROLASTIN-C LIQUID.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch, or call 1-800-FDA-1088.

PROLASTIN®-C LIQUID is an alpha1-proteinase inhibitor (human) (alpha1-PI) indicated for chronic augmentation and maintenance therapy in adults with clinical evidence of emphysema due to severe hereditary deficiency of alpha1-PI (alpha1-antitrypsin deficiency).

Limitations of Use

  • The effect of augmentation therapy with any alpha1-PI, including PROLASTIN-C LIQUID, on pulmonary exacerbations and on the progression of emphysema in alpha1-PI deficiency has not been conclusively demonstrated in randomized, controlled clinical trials
  • Clinical data demonstrating the long-term effects of chronic augmentation or maintenance therapy with PROLASTIN-C LIQUID are not available
  • PROLASTIN-C LIQUID is not indicated as therapy for lung disease in patients in whom severe alpha1-PI deficiency has not been established

PROLASTIN-C LIQUID is contraindicated in immunoglobulin A (IgA)-deficient patients with antibodies against IgA or patients with a history of anaphylaxis or other severe systemic reaction to alpha1-PI products.

Hypersensitivity reactions, including anaphylaxis, may occur. Monitor vital signs and observe the patient carefully throughout the infusion. If hypersensitivity symptoms occur, promptly stop PROLASTIN-C LIQUID infusion and begin appropriate therapy.

Because PROLASTIN-C LIQUID is made from human plasma, it may carry a risk of transmitting infectious agents, eg, viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent, and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent. This also applies to unknown or emerging viruses and other pathogens.

The most common adverse reactions during PROLASTIN-C LIQUID clinical trials in >5% of subjects were diarrhea and fatigue, each of which occurred in 2 subjects (6%).

Please see full Prescribing Information for PROLASTIN-C LIQUID.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch, or call 1-800-FDA-1088.

Important Safety Information

PROLASTIN®-C LIQUID is an alpha1-proteinase inhibitor (human) (alpha1-PI) indicated for chronic augmentation and maintenance therapy in adults with clinical evidence of emphysema due to severe hereditary deficiency of alpha1-PI (alpha1-antitrypsin deficiency).

Limitations of Use

  • The effect of augmentation therapy with any alpha1-PI, including PROLASTIN-C LIQUID, on pulmonary exacerbations and on the progression of emphysema in alpha1-PI deficiency has not been conclusively demonstrated in randomized, controlled clinical trials
  • Clinical data demonstrating the long-term effects of chronic augmentation or maintenance therapy with PROLASTIN-C LIQUID are not available
  • PROLASTIN-C LIQUID is not indicated as therapy for lung disease in patients in whom severe alpha1-PI deficiency has not been established

PROLASTIN-C LIQUID is contraindicated in immunoglobulin A (IgA)-deficient patients with antibodies against IgA or patients with a history of anaphylaxis or other severe systemic reaction to alpha1-PI products.

Hypersensitivity reactions, including anaphylaxis, may occur. Monitor vital signs and observe the patient carefully throughout the infusion. If hypersensitivity symptoms occur, promptly stop PROLASTIN-C LIQUID infusion and begin appropriate therapy.

Because PROLASTIN-C LIQUID is made from human plasma, it may carry a risk of transmitting infectious agents, eg, viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent, and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent. This also applies to unknown or emerging viruses and other pathogens.

The most common adverse reactions during PROLASTIN-C LIQUID clinical trials in >5% of subjects were diarrhea and fatigue, each of which occurred in 2 subjects (6%).

Please see full Prescribing Information for PROLASTIN-C LIQUID.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch, or call 1-800-FDA-1088.

References

  1. Campos MA, Alazemi S, Zhang G, Wanner A, Sandhaus RA. Effects of a disease management program in individuals with alpha-1 antitrypsin deficiency. COPD. 2009;6(1):31–40.