Interpreting Your Test Results
The results of your Grifols AlphaKit test are fast and confidential.
The Grifols AlphaKit determines your AAT genotype and phenotype. Your genotype is your genetic makeup. Your genotype combines with environmental factors to determine your phenotype, which is your physical characteristics, such as height, weight or alpha1 level. Learn more about the genotype-phenotype relationship.2
Testing for your genotype is efficient and automated, but it can only identify genes for which specific tests have been made. Testing for your phenotype is the most direct method of identifying Alphas and carriers.
The Grifols AlphaKit also measures AAT levels in your blood. If your level is below 82 mg/dL or 11 micromole/L, you should talk to your doctor.
Here are the more common phenotypes and their corresponding AAT levels.1
|Phenotype||AAT Blood Levels|
|MM (2 normal copies)||20–53 µM | 150–350 Mg/dL|
|MZ (1 normal copy, 1 abnormal copy)||12–28 µM | 90–210 Mg/dL|
|SS (2 marginally abnormal copies)||13–27 µM | 100–210 Mg/dL|
|SZ (1 abnormal copy, 1 marginally abnormal copy)||10–16 µM | 75–120 Mg/dL|
|ZZ (2 abnormal copies)||2.5–7 µM | 20–45 Mg/dL|
|NULLNULL (2 nonfunctional copies)||0 µM | 0 Mg/dL|
HAVE A GOOD TALK WITH YOUR DOCTOR
It's important to have a productive talk with your doctor. Use this list of questions to ask about Alpha-1. Add questions of your own. Print them out. Bring them to your appointment. Find out more about in the Doctor Discussion Guide