How Prevalent Is Alpha-1?
Alpha-1 may be more common than you think but it is rarely diagnosed.1 Up to 25 million Americans are estimated to have an abnormal gene for the production and release of AAT.2 Out of that 25 million, up to 100,000 may have Alpha-1, and 95,000 of them remain undiagnosed.3 You have Alpha-1 if you inherited an abnormal gene from both your mother and your father. Alpha-1 raises your risk of getting lung disease.2
Alpha-1 can lead to serious lung, liver, and skin diseases
If you have emphysema, asthma, chronic obstructive pulmonary disease (COPD), or chronic bronchitis, it may have been caused by Alpha-1.
Carriers are at increased risk, too
You are an Alpha-1 carrier if you inherited 1 abnormal gene from one of your parents. If you are an Alpha-1 carrier and only inherited 1 abnormal gene, compared with people with normal AAT genes, you have:
A higher-than-normal risk of lung disease2,4
ALPHA-1 DIAGNOSIS IS OFTEN MISSED
Most people with Alpha-1 suffer with symptoms diagnosed as something else. Which of these symptoms look familiar?5
- Shortness of breath
- Chronic cough and phlegm (chronic bronchitis)
- Recurring chest colds or pneumonia.