Why test for alpha-1?
Alpha-1 is the major known genetic risk factor for COPD1
Testing all COPD patients for alpha-1 can help detect those at increased risk for lung disease.
Test all adults with symptomatic emphysema, regardless of smoking history11.
Prevalence of alpha-1 in the United States
AAT deficiency is a rarely diagnosed disease10
- >100,000 people in the United States are estimated to have AAT deficiency9
- Up to 25 million Americans are thought to have at least 1 deficient allele (S or Z), and may pass that gene on to their children2