While lifestyle changes cannot cure Alpha-1, they can reduce the impact of low-AAT on your body:
Smoking increases the amount of neutrophil elastase in your lungs and may speed up the progression of lung damage. Quitting may not be easy, but it may be done. Don’t give up if your first attempt to stop smoking fails. Keep trying and chances are you will be successful. Discuss therapeutic and behavior modification programs with your doctor.1
Smoking accelerates the damage to your lungs. See what effect smoking has on your lung function and how it destroys the lung.
Second-hand smoke is dangerous if you have Alpha-1. If someone in your household smokes, ask them to stop, or step outside when smoking, or avoid them when they smoke.1
If you live in the United States, call the American Lung Association (800-LUNG-USA, 800-586-4872) or get more information about quitting on their Web site.
Prevent infections and treat them aggressively. Your body responds to infection by producing white blood cells that release neutrophil elastase, which can damage your lungs. Call your doctor at the earliest signs of cold or flu. Follow your doctor's advice for appropriate treatment. Ask about vaccines for flu and pneumonia. Avoid contact with people with colds. Washing your hands helps.1
Avoid environmental pollutants, both at home and in the workplace, if possible.
What Does It Mean To Be an Alpha-1 Carrier?
Managing Environmental Risk Factors - a brochure from AlphaNet
Alcohol puts a strain on your liver, which may already be stressed because you’re a carrier for Alpha-1. If you have established liver disease, your goal should be to eliminate alcohol.1
Weight loss is a common problem in patients with chronic lung diseases; up to 40% of patients have progressive weight loss. One theory is that carriers take in fewer calories. Another is that patients with chronic lung diseases burn more calories because they use more energy breathing. What may be enough for a person with normal lung function may not be enough for a carrier with Alpha-1. Tailor your dietary habits to your personal needs to maintain proper weight.
Routine exercise improves mental outlook, stamina and physical well-being. The long-term benefits are significant.
The right amount of exercise is different for each individual depending on their ability and goals. Think about your health and exercise goals and tailor a program to meet those goals.
What Does It Mean To Be an Alpha-1 Carrier?
Managing Environmental Risk Factors – a brochure from AlphaNet
Prolastin-C, Alpha1-Proteinase Inhibitor (Human) is for adults who have emphysema caused by inherited alpha1-antitrypsin deficiency. The effect of therapy with any alpha1-proteinase inhibitor (alpha1-PI) on pulmonary exacerbations and on the progression of emphysema in alpha1-antitrypsin deficiency has not been demonstrated in randomized, controlled clinical trials. PROLASTIN-C is not indicated as therapy for lung disease in patients in whom severe Alpha1-PI deficiency has not been established.
Prolastin-C may contain trace amounts of IgA. IgA deficient patients with antibodies against IgA should not receive Prolastin-C due to the risk of hypersensitivity.
The most common side effects during clinical trials with Prolastin-C were chills, a general feeling of being unwell, headache, rash, hot flush, and itching.
Prolastin-C is made from human plasma. Products made from human plasma may carry a risk of transmitting infectious agents, e.g., viruses, and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent.
Please see accompanying Prolastin-C Full Prescribing Information for complete prescribing details.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.