One-stop PROLASTIN-C enrollment, delivery and support

Prolastin Direct® Patient Services secures insurance authorization, coordinates infusion services, ships PROLASTIN-C directly to the location of your choice, and connects you to health management coordinators who are experienced Alpha-1 patients themselves. Find out more about Prolastin Direct® Patient Services now

Dosing & Administration of PROLASTIN-C

PROLASTIN-C is a medicine that is given through a needle into a vein. While it is a prescription medicine, PROLASTIN-C is not a prescription you pick up at your pharmacy. PROLASTIN-C is shipped directly to you, to your doctor, or to an infusion center authorized by you and your doctor.1

The dosing of PROLASTIN-C is based on how much you weigh. The recommended dose is 60 milligrams for each kilogram (2.2 pounds) of your body weight given once a week.1

You can receive PROLASTIN-C at a rate of up to 0.08 milliliters for each kilogram per minute. The average infusion takes about 15 minutes to infuse.1

No refrigeration necessary

PROLASTIN-C does not need to be refrigerated and can be stored at room temperature, but the temperature should not exceed 25°C (77°F). You should also avoid freezing PROLASTIN-C because the bottle holding the diluent (sterile water) might break.1

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Important Safety Information

Prolastin-C, Alpha1-Proteinase Inhibitor (Human) is for adults who have emphysema caused by inherited alpha1-antitrypsin deficiency. The effect of therapy with any alpha1-proteinase inhibitor (alpha1-PI) on pulmonary exacerbations and on the progression of emphysema in alpha1-antitrypsin deficiency has not been demonstrated in randomized, controlled clinical trials. PROLASTIN-C is not indicated as therapy for lung disease in patients in whom severe Alpha1-PI deficiency has not been established.

Prolastin-C may contain trace amounts of IgA. IgA deficient patients with antibodies against IgA should not receive Prolastin-C due to the risk of hypersensitivity.

The most common side effects during clinical trials with Prolastin-C were chills, a general feeling of being unwell, headache, rash, hot flush, and itching.

Prolastin-C is made from human plasma. Products made from human plasma may carry a risk of transmitting infectious agents, e.g., viruses, and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent.

Please see accompanying Prolastin-C Full Prescribing Information for complete prescribing details.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

  1. PROLASTIN-C [package insert]. Grifols