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It is important to talk to your doctor if you have any questions about alpha1-antitrypsin (AAT) deficiency or your health. To get started, print the list of questions below and add any additional questions you wish to discuss with your doctor. Bring the printout with you to your doctor's appointment to help you and your doctor determine if you should be tested for AAT deficiency.
Do I have symptoms of AAT deficiency?
Considering my family history, is it possible I may have inherited AAT deficiency?
Do I have a condition that may be caused by AAT deficiency, such as asthma, liver disease, or chronic obstructive pulmonary disease (COPD)?
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Important Safety Information
Prolastin®, Alpha1-Proteinase Inhibitor (Human) is indicated for chronic replacement therapy of individuals having congenital deficiency of alpha-1 PI (alpha1-antitrypsin deficiency) with clinically demonstrable panacinar emphysema. Weekly Prolastin® therapy has demonstrated a low occurrence of side effects. In clinical studies with Prolastin®, reactions were observed in 1.16% of infusions, the most common events being fever (0.77%), light-headedness (0.19%), and dizziness (0.19%). As with all plasma-derived therapeutics, the potential to transmit infectious agents cannot be totally eliminated. Individuals with selective IgA deficiencies who have known antibody against IgA (anti-IgA antibody) should not receive Prolastin®, since these patients may experience severe reactions, including anaphylaxis, to IgA which may be present.
You are encouraged to report negative side effects of prescription drugs
to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Please click here for Prolastin® full Prescribing Information.
Remember, your doctor or healthcare provider is the single best source of information regarding you and your health. Please consult your doctor or healthcare provider if you have any questions about your health or any of your medications.
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